The Immortalists is the story of two eccentric scientists struggling to create eternal youth with medical breakthroughs in a world they call "blind to the tragedy of old age." Bill Andrews is a lab biologist and famed long-distance runner racing against the ultimate clock. Aubrey de Grey is a genius theoretical biologist who conducts his research with a beer in hand. They differ in style and substance, but are united in their common crusade, cure aging or die trying. They publicly brawl with the old guard of biology who argue that curing aging is neither possible nor desirable. As Andrews and de Grey battle their own aging and suffer the losses of loved ones, their journeys toward life without end ultimately become personal.